Reports Outline Crohn's Disease Study Results from Shanghai (Development and validation of a novel therapeutic drug monitoring-based nomogram for prediction of primary endoscopic response to anti-TNF therapy in active Crohn's disease).

Předmět:
Zdroj: Gastroenterology Week; 6/21/2024, p2178-2178, 1p
Abstrakt: A study conducted in Shanghai, China explored the correlation between serum anti-tumor necrosis factor (TNF) levels and early endoscopic response in patients with active Crohn's disease (CD). The study found that higher levels of infliximab (IFX) and adalimumab (ADA), two anti-TNF monoclonal antibodies, were associated with endoscopic response in CD patients. The researchers developed a nomogram prediction model based on laboratory markers and therapeutic drug monitoring (TDM) to evaluate the primary endoscopic response to anti-TNF therapy. This study provides valuable insights for optimizing treatment strategies and switching therapy in CD patients. [Extracted from the article]
Databáze: Complementary Index