| Autor: |
Westra, Jeroen M., Zwakenberg, Manon A., Halmos, Gyorgy B., van der Laan, Bernard F. A. M., van der Vegt, Bert, Plaat, Boudewijn E. C. |
| Předmět: |
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| Zdroj: |
Clinical Otolaryngology; Jul2024, Vol. 49 Issue 4, p429-435, 7p |
| Abstrakt: |
Objective: To assess whether narrow band imaging (NBI) detects fields of cancerisation around suspicious lesions in the upper aerodigestive tract, which were undetected by white light imaging (WLI). Methods: In 96 patients with laryngeal and pharyngeal lesions suspicious for malignancy, 206 biopsies were taken during laryngoscopy: 96 biopsies of suspicious lesions detected by both WLI and NBI (WLI+/NBI+), 60 biopsies adjacent mucosa only suspicious with NBI (WLI‐/NBI+), and 46 biopsies of NBI and WLI unsuspicious mucosa (WLI‐/NBI‐) as negative controls. Optical diagnosis according to the Ni‐classification was compared with histopathology. Results: Signs of (pre)malignancy were found in 88% of WLI+/NBI+ biopsies, 32% of WLI‐/NBI+ biopsies and 0% in WLI‐/NBI‐ (p <.001). In 58% of the WLI‐/NBI+ mucosa any form of dysplasia or carcinoma was detected. Conclusion: The use of additional NBI led to the detection of (pre)malignancy in 32% of the cases, that would have otherwise remained undetected with WLI alone. This highlights the potential of NBI as a valuable adjunct to WLI in the identification of suspicious lesions in the upper aerodigestive tract. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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