Direct C–H alkylation of 3,4-dihydroquinoxaline-2-ones with N-(acyloxy)phthalimides via radical–radical cross coupling.

Autor: Hota, Sudhir Kumar, Singh, Gulshan, Murarka, Sandip
Předmět:
Zdroj: Chemical Communications; 6/21/2024, Vol. 60 Issue 49, p6268-6271, 4p
Abstrakt: We present an organophotoredox-catalyzed direct Csp3–H alkylation of 3,4-dihydroquinoxalin-2-ones employing N-(acyloxy)pthalimides to provide corresponding products in good yields. A broad spectrum of NHPI esters (1°, 2°, 3°, and sterically encumbered) participates in the photoinduced alkylation of a variety of 3,4-dihydroquinoxalin-2-ones. In general, mild conditions, broad scope with good functional group tolerance, and scalability are the salient features of this direct alkylation process. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index