Short-course Radiotherapy for Airway Stenting in Malignant Airway Obstruction: A Case Report and Literature Review.

Autor: FACONDO, GIUSEPPE, REVERBERI, CHIARA, CESCHIA, TINO, PARISI, GIUSEPPE, VULLO, GIANLUCA, MORETTI, EUGENIA, TROVÒ, MARCO
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Zdroj: Cancer Diagnosis & Prognosis; May/Jun2024, Vol. 4 Issue 3, p359-362, 4p
Abstrakt: Background: Malignant airway obstruction (MAO) secondary to tumor growth occurs in nearly a third of patients with lung cancer and portends a very poor prognosis if untreated. Treatment options include bronchoscopic intervention with tumor debulking, stent placement, endobronchial brachytherapy, or palliative radiotherapy. Case Report: This is a report of a 74-year-old woman with a medical history of metastatic lung adenocarcinoma, hospitalized for dyspnea, hemoptysis, and chest pain with a radiographic finding of MAO on chest Xray and computed tomography. Patient underwent radiation with a total dose of 13 Gy in two once-weekly fractions of 6.5 Gy per fraction. Three days after the end of radiation treatment, chest X-ray showed a completely right lung reexpansion without atelectasis. Two weeks after radiotherapy treatment, the patient was discharged from hospital without pulmonary symptoms. Conclusion: A different fractionation with a lower equivalent dose in 2 Gy fraction compared to literature data showed efficacy in resolving MAO with excellent local control in the first three months of follow-up. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index