Autor: |
Pażyra, Aldona, Stanicki, Paweł, Szarpak, Julita, Kusak, Natalia, Żak, Natalia, Jaworska, Barbara |
Předmět: |
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Zdroj: |
Journal of Education, Health & Sport; Oct2024, Vol. 69, p1-14, 14p |
Abstrakt: |
Background: In 2019, according to WHO estimates, 262 million people were affected by asta, resulting in 455,000 deaths [1]. Asthma, is a chronic inflammatory disease of the airways that causes reversible bronchoconstriction, making it difficult for patients to breathe. Exacerbations of the disease can be caused by a variety of factors but share similar symptoms such as wheezing, coughing, shortness of breath and chest tightness. Severe asthma exacerbations are defined as symptoms that do not respond to inhaled medications and improve only after oral or intravenous steroid administration. Asthma-related deaths often occur during exacerbations. Vitamin D, which is produced naturally in the body and found in some foods, is a steroid-derived vitamin. Adequate doses of this vitamin, administered through medication or supplements, can be used to maintain its proper levels in the organism. Vitamin D is essential for regulating calcium levels in the body and for bone remodeling. It also has immunomodulatory effects, affecting both innate and adaptive immunity. This partly explains its association with changes in the airway epithelium that occur as a result of inflammation in asthma. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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