| Autor: |
FU Le-yao, YANG Ting-ting, LI Fu-ping, TIAN Run, ZHANG Lu, SONG Gui-shuang, LIAO Jun-hao, ZENG Si-xuan, YU Chuan, XIAO Cheng-han, LIU Zhen-mi |
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| Zdroj: |
Modern Preventive Medicine; 2024, Vol. 51 Issue 10, p1766-1774, 9p |
| Abstrakt: |
Objective To examine the association between exposure to ambient PM2.5 chemical components and semen quality in Southwest China. Methods We conducted a longitudinal study to investigate 1 105 sperm donors who lived in Sichuan Province, China and underwent semen examination in Sichuan Province human sperm bank from October 2019 to December 2021.Exposure to ambient PM2.5 and its chemical components in lag 0-90 d, lag 0-9 d, lag 10-14 d and lag 70-90 d were assessed by extracting monthly PM2.5 and its chemical components values from a few validated grid datasets at each subject's residential address. Spearman rank correlation analysis was used to evaluate the correlation between PM2.5 and its chemical components. A linear mixed-effects model was used to analyze the relationship between exposure to PM2.5 chemical components and semen quality parameters. Results PM2.5 is highly positively correlated with its chemical components. PM2.5, NH4+, SO42-, NO3-, OM, and BC exposures were significantly associated with decreased total motility (P < 0.05). OM exposure was significantly associated with decreased in sperm progressive motility (P < 0.05), and the mean change in sperm progressive motility was -1.166 (95% CI: -2.174 -- -0.171) for per IQR (3.1 µg/m³) increase in OM. Conclusion PM2.5 and its chemical components are risk factors for sperm total motility. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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