| Abstrakt: |
Objective To analyze the epidemiological trends of Alzheimer's disease in the elderly population in China from 1990 to 2019, and to provide a scientific basis for the specific formulation of prevention and treatment measures. Methods Based on data obtained from the Global Burden of Disease (GBD) 2019 database, we analyzed quantitative changes in the number of incidences and disability-adjusted life years (DALYs) of Alzheimer's disease among people aged 60 to 89 years in China from 1990 to 2019. Trend changes over the period were assessed by calculating the annual percentage change (AAPC) and linkage regression analysis, age-period-cohort models were constructed by Statal7 to analyze trends in DALY incidence and rates along three dimensions: age, period, and cohort. Results The number of DALY and Alzheimer's disease incidence cases in the Chinese elderly population in 2019 was 1 526 516 and 5 034 024 person-years, respectively, with 5 829 523 and 1 956 623 person-years of DALY and Alzheimer's disease incidence in elderly men, and 943 563 and 3 077 401 person-years of DALY and Alzheimer's disease incidence in elderly women, respectively. The Chinese elderly population in 2019 Incidence and DALY rates were 600.49 per 100 000 and 1 980.23 per 100 000, respectively, increasing at an average rate of 1.12% and 0.81% per year, with a more pronounced increase in elderly men than in elderly women. Conclusion China's elderly population faces a heavy burden of disease from Alzheimer's disease, and the government should take immediate action to alleviate the heavy morbidity and financial burden on patients. [ABSTRACT FROM AUTHOR] |
