| Abstrakt: |
A recent study conducted by researchers at Aix-Marseille University in Marseille, France, has shed light on the underlying causes of Charcot-Marie-Tooth (CMT) disease, a common inherited neurological disorder. The study found that an imbalance in the Nrg1-erbb2/3 signaling pathway, which is responsible for myelination in the peripheral nervous system, is linked to aberrant myelination in CMT4H, a demyelinating form of CMT disease. The researchers also identified a potential therapeutic strategy for reducing CMT4H pathology by modulating the Nrg1-erbb2/3 pathway. This research provides valuable insights into the mechanisms of CMT disease and offers potential avenues for future treatment options. [Extracted from the article] |
