Study Findings on Colon Cancer Described by Researchers at Department of Radiology and Nuclear Medicine (Identification of a 5-Gene Cuproptosis Signature Predicting the Prognosis for Colon Adenocarcinoma Based on WGCNA).

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Zdroj: Cancer Weekly; 6/11/2024, p1459-1459, 1p
Abstrakt: Researchers from the Department of Radiology and Nuclear Medicine in Heilongjiang, China have identified a 5-gene signature that can predict the prognosis for colon adenocarcinoma. The study used gene expression data from the Gene Expression Omnibus and The Cancer Genome Atlas to construct a gene coexpression network and identify critical genes related to cuproptosis, a copper-dependent form of cell death. The identified gene signature was validated and found to be a more reliable prognostic factor than clinical factors such as age and stage of disease. These findings provide a foundation for further research into cuproptosis-related biomarkers for predicting colon adenocarcinoma prognosis. [Extracted from the article]
Databáze: Complementary Index