| Autor: |
Qi, Dake, Sun, Yingying, Hu, Bingying, An, Hai, Lin, Haiyang, Fang, Jinjun, Wei, Yang |
| Předmět: |
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| Zdroj: |
Acta Chromatographica; 2024, Vol. 36 Issue 2, p99-105, 7p |
| Abstrakt: |
SZJ-1207 is an antidepressant natural product with a steroidal structure extracted from Stephanotis mucronata. It is a novel antidepressant candidate molecule and all its pharmacokinetic properties have not been reported. In this pharmacokinetic study in mice following oral administration, an accurate and sensitive UPLC-MS/MS method was established and evaluated to measure SZJ-1207 concentrations in mouse plasma and brain samples. The results provide information regarding the pharmacokinetics of SZJ-1207 as a potential antidepressant. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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