| Autor: |
Aleksandrova, A. M., Cherednichenko, A. S., Rassukana, Yu. V. |
| Předmět: |
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| Zdroj: |
Journal of Organic & Pharmaceutical Chemistry / Zhurnal Organichnoi ta Farmatsevtichnoi Khimii; 2023, Vol. 21 Issue 4, p36-42, 7p |
| Abstrakt: |
A simple preparative approach to a series of functionalized dimethylphosphinoyl-containing cyclopropanes and cyclobutanes has been developed; it is based on cyclocondensation of dimethylphosphinoyl acetonitrile with 1,2- and 1,3-dibromoalkanes. Synthetic procedures for obtaining nitriles, amines and carboxylic acids containing in their structure small saturated cyclic rings of cyclopropane or cyclobutane and a dimethylphosphine oxide fragment, which are popular in drug design, have been developed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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