| Autor: |
Karahutová, Lívia, Bujňáková, Dobroslava |
| Zdroj: |
Veterinary Research Communications; Jun2024, Vol. 48 Issue 3, p1899-1905, 7p |
| Abstrakt: |
In our study antibacterial and anti-biofilm efficacy of 2 inorganics (Zn(II) sulphate monohydrate; Zn(II) sulphate heptahydrate) and 3 organic Zn(II) substances (Zn(II) chelate of protein hydrolysate: Zn-Bio; Zn(II) chelate of amino acid hydrate: Zn-AMK; Zn(II) chelate of glycine hydrate: Zn-Gly) were explored and compared against multidrug resistant Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Klebsiella oxytoca (K. oxytoca) and Pseudomonas aeruginosa (P. aeruginosa) using by the 96- wells microtiter plate-based resazurin and/or crystal violet assay. Our finding confirmed that Zn(II)-sulphates and Zn(II)-amino acid complexes exhibit dose and genus-based antibacterial and anti-biofilm potential. Organic compounds (Zn-AMK and Zn-Gly) were more effective against bacterial growth, except P. aeruginosa. Besides Zn-AMK, others organic and inorganic forms of Zn(II) caused predominantly statistically significant decrease of biofilm production in all of tested bacteria. Current data highlights that Zn(II) in various forms has a great potential to be developed as antibacterial and anti-biofilm agents. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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