| Autor: |
Abd Al-Kadhim, Saja Hassan, Mohammed, Jabbar Abadi |
| Předmět: |
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| Zdroj: |
Veterinary Medicine & Public Health Journal; 2024 Special Issue, Vol. 5, p120-124, 5p |
| Abstrakt: |
Objectives: The purpose of the research was to see how a nano-extract (zinc oxide) of oleander leaves affected the histological structure of the liver in male laboratory mice aged (7-8) weeks and weighing (28-35 g). Methods: They were split up into three groups, with ten mice in each. The control group made the first group. The second group was treated with an oleander leaf nano-extract at a concentration of (20 mg/kg). The group that was administered a 30 mg/kg dosage of oleander leaf nano-extract is the third group. For 30 to 45 days on a daily basis, a (30 mg/kg) concentration of the oleander leaf nano-extract was used. Half of the rodents were sacrificed at the end of the initial thirty days, and histological sections of the liver were obtained. Results: Histological sections of the liver were obtained from the residual half, which was sacrificed after 45 days when the experiment ended. Animals injected with a Nano-extract of oleander leaves at a dose of (20 mg/kg) for 40 days had aberrant liver structure, cells, and histological abnormalities. Animals that received a 45-day injection of a (30 mg/kg) dosage of oleander leaf nano-extract also had pathological alterations and aberrant liver and central vein cell morphology. Conclusions: The results showed the toxic effects of the Nano-extract of the oleander plant and the xistence of histological alterations in the histological structure of the liver in groups treated with varying amounts of oleander leaf nano-extract. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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