Chest radiographic thoracic areas and respiratory outcomes in infants with anterior abdominal wall defects.
| Autor: | Jenkinson, Allan, Krishnan, Mirna, Davenport, Mark, Harris, Christopher, Dassios, Theodore, Greenough, Anne |
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| Předmět: |
LUNG abnormalities
ABDOMINAL abnormalities GASTROSCHISIS BRONCHOPULMONARY dysplasia CHEST X rays DESCRIPTIVE statistics PRENATAL care DURATION of pregnancy GESTATIONAL age RESPIRATORY organ physiology UMBILICAL hernia BIRTH weight SENSITIVITY & specificity (Statistics) DISEASE risk factors DISEASE complications CHILDREN |
| Zdroj: | Journal of Perinatal Medicine; Jun2024, Vol. 52 Issue 5, p552-555, 4p |
| Abstrakt: | Infants with anterior abdominal wall defects (AWD) can suffer from pulmonary complications. Our aims were to determine if the chest radiographic thoracic areas (CRTAs) on day one differed between infants with exomphalos or gastroschisis, whether this related to differing severity of outcomes and if they were lower than those of controls indicating abnormal antenatal lung growth. A review of infants with exomphalos or gastroschisis born between January 2004 and January 2023 was conducted. The control group was term, newborn infants ventilated for poor respiratory drive at birth. Chest radiographs on day one were analysed and the highest CRTA in the first 24 h after birth for each infant included in the analysis. The 127 infants with gastroschisis had a lower gestational age and birthweight than the 62 exomphalos infants and 130 controls (all p<0.001) The CRTAs of the controls were greater than the CRTAs of the exomphalos and the gastroschisis infants (p = 0.001). The median CRTA corrected for birthweight was lower in the exomphalos infants [688, IQR 568-875 mm2/kg] than the gastroschisis infants [813, IQE 695-915 mm2/kg] No gastroschisis infant developed bronchopulmonary dysplasia (BPD). A CRTA of 1759 mm2 had a sensitivity of 81 % and specificity of 71 % in predicting BPD in infants with exomphalos. Infants with gastroschisis or exomphalos had lower CRTAs than controls suggesting both groups had abnormal antenatal lung development. The CRTA was lower in the exomphalos infants who also had worse respiratory outcomes, hence CRTA assessment may a useful prognostic aid. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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