New Ovarian Cancer Findings from University of Pittsburgh Outlined (Gpx3 Supports Ovarian Cancer Tumor Progression In Vivo and Promotes Expression of Gdf15).

Předmět:	OVARIAN cancer GENE expression OVARIAN tumors CANCER invasiveness IMMUNE checkpoint inhibitors
Zdroj:	Women's Health Weekly; 6/6/2024, p688-688, 1p
Abstrakt:	New research from the University of Pittsburgh has found that the protein GPX3 plays a role in the progression of ovarian cancer. The study showed that GPX3 is necessary for tumor growth in vivo and regulates the expression of GDF15, a growth factor associated with oncogenic and immune modulatory activities. The researchers also found that GPX3 expression is correlated with immune cell signatures and PD-L1 expression, suggesting that it may be a marker for ovarian tumors susceptible to immune checkpoint inhibitors. This research provides new insights into the mechanisms of ovarian cancer and potential therapeutic targets. [Extracted from the article]
Databáze:	Complementary Index
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