University of Toronto Reports Findings in Loeys-Dietz Syndrome (Impact of Genotype-Phenotype Interactions on Cardiovascular Function in Paediatric Loeys-Dietz Syndrome).

Předmět:	PEDIATRICS THORACIC aorta SYNDROMES SINUS of valsalva DISSECTING aneurysms
Zdroj:	Pediatrics Week; 6/7/2024, p555-555, 1p
Abstrakt:	A recent study conducted by the University of Toronto examined the impact of genotype-phenotype interactions on cardiovascular function in pediatric Loeys-Dietz Syndrome (LDS) patients. The study found that patients with certain mutations had more severe cardiovascular phenotypes, including larger aortic dimensions and increased aortic stiffness. These findings suggest that genotypes should be considered in the clinical management of pediatric LDS patients. The study provides valuable insights into the relationship between genotype and phenotypical vascular and cardiac properties in LDS patients. [Extracted from the article]
Databáze:	Complementary Index
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