| Abstrakt: |
A recent study from the Beijing Institute of Technology explores the use of organ-on-a-chip technology in pharmaceutics. The researchers highlight the importance of lymph nodes in assessing the immunotoxicity of new drugs and propose the use of organ chips to accurately simulate the complex microstructure of lymph nodes and the interactions between immune cells. The study discusses the applications of these systems in modeling immune cell motility, cell-cell interactions, vaccine responses, drug testing, and cancer research. The researchers also identify challenges in simulating the structure, cell source, and extracellular matrix of lymph nodes and provide an outlook on the future direction of integrated immune system chips. [Extracted from the article] |
