| Autor: |
Costa de Menezes, Manuela, Cesário, Bruna C., Félix, Natanael S., Silva, Renato L. B., Sousa, Daniela R. F., Silva, Francisco H. A., Viana, Geysa A., Silva, Emerson C. O., Bezerra, Lorena S., Rodrigues, Victor Hugo V., Teófilo, Tiago da Silva, Batista, Jael Soares |
| Zdroj: |
Journal of Apicultural Research; Jun2024, Vol. 63 Issue 3, p549-555, 7p |
| Abstrakt: |
The objective of this study was to evaluate the levels of phenols, total flavonoids, as well as the antioxidant, genoprotective, and photoprotective activities of the red propolis ethanolic extract produced by Apis mellifera. Different concentrations of the extract were analyzed In vitro by spectrophotometry. The photoprotective effect of the extract was evaluated In vivo in 30 Wistar rats divided into three groups: Group 1 - the skin received no topical application of the extract and was not subjected to ultraviolet irradiation; Group 2 - the skin was not subjected to topical application of the extract and was irradiated; Group 3 – the skin underwent topical application of the extract and was irradiated. The skin was evaluated macroscopically, and the density of inflammatory cells, mast cells, necrotic cells, and collagen fibers were quantified. The extract contained high levels of phenols and flavonoids, with antioxidant and genoprotective capacity, protecting the skin from irradiation. In group II, erythemas, blisters, and superficial crusting were observed. No significant differences in mean values of mast cell density and collagen fibers were observed between groups I and III. It was concluded that the ethanolic extract of red propolis exerted genoprotective and photoprotective effects by promoting satisfactory absorbance of ultraviolet radiation and was able to protect the skin from lesions induced by UVB irradiation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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