Clinico-Epidemiological Characteristics of Healthcare Workers with SARS-CoV-2 Infection during the First and Second Waves in a Teaching Hospital from Eastern India: A Comparative Analysis.

Autor: Singh, Arvind Kumar, Panigrahi, Manoj Kumar, Pradhan, Somen Kumar, Pal, Debkumar, Subba, Sonu H., Patro, Binod Kumar, Behera, Binod Kumar, Mishra, Baijayantimala, Behera, Bijayini, Mohapatra, Prasanta Raghab, Bhuniya, Sourin, Bal, Shakti Kumar, Sarkar, Saurav, Pillai, Jawahar S. K, Mohanty, Sachidananda, Gitanjali, Batmanabane
Předmět:
Zdroj: Hospital Topics; Apr-Jun2024, Vol. 102 Issue 2, p84-95, 12p
Abstrakt: In this retrospective observational study, we have performed a comparative analysis of the demographic, clinical and epidemiological characteristics of the HCWs affected with SARS-CoV-2 infection during first two waves in India. The overall prevalence of SARS-CoV-2 infection among HCWs was found to be 15.24% (14.20–16.33) and 23.38% (22.14–25.65) during first and second waves respectively. The second wave showed an adjusted odds ratio of 0.04(0.02–0.07) and 2.09(1.49–2.93) for hospitalization and being symptomatic, respectively. We detected significantly higher level of C-reactive protein (CRP) among admitted HCWs during the second wave (5.10 –14.60 mg/dl) as compared to the first wave (2.00 – 2.80 mg/dl). Our study found the relative risk of SARS-CoV-2 reinfection among HCWs during the second wave to be 0.68 [0.57–0.82, p < 0.001)]. Although, the prevalence of SARS CoV-2 infection and risk of being symptomatic was higher during second wave, the risk of hospitalization was less when compared with the first wave. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index