| Autor: |
Gnanaoli, Karthiyayini, Rajkumar, Deepan Babu, Gopal, Keerthana, Saritha, B., Maheswari, C. Uma |
| Předmět: |
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| Zdroj: |
European Journal of Organic Chemistry; 5/27/2024, Vol. 27 Issue 20, p1-6, 6p |
| Abstrakt: |
A facile, one‐pot sequential synthesis of highly substituted pyrrole employing TBAI/TBHP has been developed from readily available precursors. β‐Enaminones generated in situ from β‐ketoesters and primary amines react sequentially with electron‐deficient alkynes via a radical pathway to form the penta‐substituted pyrroles in moderate to good yields. This strategy for the synthesis of highly functionalized pyrroles can be scaled up and shows tolerance to a variety of amines. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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