| Autor: |
Stengl, R., Benke, K., Stark, KA., Bai, Y., Radovits, T., Loganathan, S., Korkmaz-Icöz, S., Csonka, M., Karck, M., Szabó, G., Veres, G. |
| Předmět: |
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| Zdroj: |
Thoracic & Cardiovascular Surgeon; 2024 Supplement1, Vol. 72, pS1-S68, 68p |
| Abstrakt: |
This article discusses the potential benefits of preconditioning with a zinc-aspirin complex in reducing endothelial damage in arterial grafts used in coronary artery bypass grafting (CABG). The study, conducted on rodents, compared the effects of zinc-aspirin, aspirin, and a placebo on the grafts. The results showed that both aspirin and zinc-aspirin preconditioning improved endothelial function and reduced nitro-oxidative stress and cell apoptosis. However, zinc-aspirin was found to be more effective in reducing ischemia-reperfusion injury (IRI) compared to aspirin alone. The findings suggest that zinc-aspirin preconditioning could be a promising option for improving the outcomes of CABG by preserving the function and structural integrity of arterial grafts. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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