| Autor: |
Fernanda Maria Silveira Souto, Ruy Felippe Brito Gonçalves Missaka, Marcelo Mendes Lavezzo, Priscilla Figueiredo Campos Nóbrega, Viviane Mayumi Sakata, Maria Kiyoko Oyamada, Carlos Eduardo Hirata, Joyce Hisae Yamamoto |
| Předmět: |
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| Zdroj: |
Ocular Immunology & Inflammation; May2024, Vol. 32 Issue 4, p384-390, 7p |
| Abstrakt: |
Aims: To investigate the changes in quality-of-life (QoL) metrics at a 24-month interval in non-acute VKHD patients and their association with inflammation, treatment, and visual function. Methods: SF-36 and VFQ-25 questionnaires were administered at two 24-month-apart moments to 22 non-acute VKHD patients followed for ≥12 months since acute disease onset. "Improvement," "unchanged," or "worsening" in questionnaires scores (difference >5-point) between M1 and M2 and their associations were sought. Results: Absence of systemic treatment or optic disc hyperfluorescence was associated with improved general health (SF-36). Improvement in binocular contrast sensitivity resulted in better ocular pain score; absence of anterior uveitis relapse, stable fundus findings, no use of cyclosporine or no intravitreal injections resulted in unchanged/better dependency score; no intravitreal injections resulted in unchanged/better mental health score (VFQ-25). Conclusion: Stability/improvement in QoL scores was associated with controlled inflammation, better visual function, and no need for treatment. Subclinical inflammatory signs did not impact QoL scores. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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