| Autor: |
Rubino, Raffaella, Trizzino, Marcello, Pipitò, Luca, Sucato, Giuseppe, Santoro, Marco, Maugeri, Rosario, Iacopino, Domenico Gerardo, Giammanco, Giovanni Maurizio, Siragusa, Sergio, Cascio, Antonio |
| Předmět: |
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| Zdroj: |
Antibiotics (2079-6382); May2024, Vol. 13 Issue 5, p432, 9p |
| Abstrakt: |
Ventriculitis and nosocomial meningitis caused by carbapenem-resistant Gram-negative and vancomycin-resistant Gram-positive bacteria represent a growing treatment challenge. A case of ventriculitis and bacteremia caused by carbapenem-resistant, KPC-producing Klebsiella pneumoniae and vancomycin-resistant Enterococcus faecium in a young woman with acute leukemia who was successfully treated with meropenem/vaborbactam (MVB), rifampicin, and linezolid is described in this paper. This case report emphasizes the importance of a multidisciplinary strategy, including infectious focus control, for the treatment of device-associated central nervous system (CNS) infections from multidrug-resistant bacteria. Considering the novel resistance patterns, more research on drug penetration into the central nervous system, as well as on the necessity of association therapies, is needed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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