Sensitivity of urinary antigen test in relation to clinical severity in a large outbreak of Legionella pneumonia in Spain.

Autor: Blázquez, R. M., Espinosa, F. J., Martínez-Toldos, C. M., Alemany, L., García-Orenes, M. C., Segovia, M.
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Zdroj: European Journal of Clinical Microbiology & Infectious Diseases; Jul2005, Vol. 24 Issue 7, p488-491, 4p
Abstrakt: Presented here are the results of Legionella urinary antigen testing correlated with patient characteristics and severity of pneumonia (Fine score) in 295 patients diagnosed with Legionella pneumonia in connection with a large outbreak in Murcia, Spain. Overall, the sensitivity of the urinary antigen test was 47.7% (141/295). A statistically significant association was found between the clinical severity of pneumonia and test sensitivity; 85.7% for patients with severe pneumonia versus 37.9% for patients with mild pneumonia (risk ratio, 2.3). Variables significantly associated with test positivity in multivariate analysis were as follows: pre-existing pulmonary disease, body temperature >40°C, leukocytosis and multilobar infiltrates. Patients with mild pneumonia may go undiagnosed if the urinary antigen test is used alone. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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