Abstrakt: |
A recent report from Utrecht University discusses the urgent need for innovative antiviral strategies against respiratory zoonotic RNA viruses, such as influenza A and coronaviruses. The researchers highlight the potential of single-domain antibodies (sdAbs), also known as nanobodies or VHHs, derived from camelids, as promising tools to combat these viral threats. The unique structure and attributes of sdAbs, including robustness, compact size, and cost-effectiveness, make them strong alternatives to traditional monoclonal antibodies. The report explores techniques to enhance sdAb antiviral potency and diverse administration strategies, while acknowledging the challenges in this field. [Extracted from the article] |