| Abstrakt: |
A patent application has been submitted for a pharmaceutical composition that uses lipid nanoparticles (LNPs) to deliver mRNA vaccines. The composition allows for the expression of complex antigens, eliminating the need for complex manufacturing processes. The LNPs consist of specific ratios of cationic lipid, PEGylated lipid, cholesterol-based lipid, and helper lipid. The composition can be used to elicit immune protection and may be formulated for various routes of administration. The patent application also includes methods of preparing the composition and using it to prevent or reduce symptoms of influenza infection. [Extracted from the article] |
