Sinonasal Tumors Masquerading as Invasive Fungal Sinusitis (IFS).
| Autor: | Pak, Kaitlynne Y., Hsue, Victor B., Lee, Matthew K., Chen, Michelle M., Balzer, Bonnie, Wu, Arthur W., Tang, Dennis M. |
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| Předmět: |
PARANASAL sinus surgery
RADIOTHERAPY PARANASAL sinus cancer EXTRANODAL NK-T-cell lymphoma BIOPSY SOFT tissue infections TRANSPLANTATION of organs tissues etc. CANDIDA EDEMA PARANASAL sinuses COMPUTED tomography SKULL base NECROSIS IMMUNOCOMPROMISED patients SINUSITIS ENDOSCOPIC surgery AMOXICILLIN METHICILLIN-resistant staphylococcus aureus CRANIOTOMY TREATMENT effectiveness CANCER chemotherapy NUMBNESS ADJUVANT chemotherapy NEUROENDOCRINE tumors CO-trimoxazole VORICONAZOLE SMELL disorders DIABETES ENDOSCOPY MOLECULAR diagnosis IMMUNOSUPPRESSION CEFTRIAXONE |
| Zdroj: | Annals of Otology, Rhinology & Laryngology; Jun2024, Vol. 133 Issue 6, p625-627, 3p |
| Abstrakt: | Objectives: Fungal tissue invasion in the setting of sinonasal malignancy has been rarely described in the literature. Only a handful of studies have discussed cases of suspected chronic and acute IFS (CIFS and AIFS, respectively), having an underlying undifferentiated sinonasal carcinoma, sinonasal teratocarcinosarcoma, and NK/T-cell lymphoma. Methods: Here, we describe 3 cases of carcinoma mimicking IFS from a single institution. Results: Each of our patients presented with sinonasal complaints as an outpatient in the setting of immunosuppression. Intranasal biopsies consistently were predominated by necrotic debris, with and without fungal elements, ultimately leading to a delay of oncologic care. The final pathologies included NK/T-cell lymphoma and SNEC. All patients were followed by radiation and chemotherapy, with 1 case of mortality. Conclusions: We aim to emphasize the importance of obtaining viable tissue as pathology specimens as the presence of necrosis with fungal elements may limit the diagnosis and ultimately delay the care of an underlying sinonasal carcinoma. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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