The predictive role of MRI cognitive biopsy for gleason score on radical prostatectomy material.

Autor: ÖNER, Süleyman, BOSTANCI, Yakup, GÜLŞEN, Murat, ÖZDEN, Ender, YAKUPOĞLU, Yarkın Kamil, SARIKAYA, Şaban
Předmět:
Zdroj: Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi; Mar2024, Vol. 41 Issue 1, p138-142, 5p
Abstrakt: Enhancements in the concordance between prostate biopsy results and radical prostatectomy (RP) specimens are expected to improve both oncological and functional outcomes for patients. This study aimed to assess the level of agreement in Gleason scores between biopsy specimens and RP materials in individuals who underwent magnetic resonance imaging (MRI) cognitive + systematic biopsy or only systematic biopsy. 73 patients who underwent RP between November 2015 and November 2017 were included in the study. Four patients who received chemotherapy before RP were excluded from the study. While MRI cognitive+systematic biopsy was performed in 38 patients, only systematic biopsy was performed in 31 patients. In the last stage, histopathological results of MRI cognitive + systematic biopsy, only systematic biopsy and RP specimens were compared retrospectively. When compared according to RP results, Gleason score was decreased in 5 (13.2%) of 38 patients who underwent MRI cognitive + systematic biopsy, did not change in 22 patients (57.9%) and was increased in 11 (28.9%) patients. Of the 31 patients who underwent only systematic biopsy, Gleason score decreased in 2 patients (6.5%), remained unchanged in 10 patients (32.3%), and increased in 19 patients (61.3%). Statistically significant difference was found between those who underwent MRI cognitive+systematic biopsy and those who only underwent systematic biopsy in terms Gleason score concordance according to the RP result (p=0.026). Gleason grade of tumors after RP can be more accurately predicted with MRI cognitive + systematic biopsy. Thus, surgical success may increase (necessity of lymph node dissection, etc.). For this reason, we think that MRI cognitive + systematic biopsy should be performed in patients with suspected PCa. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index