Abstrakt: |
A recent study conducted at Worcester Polytechnic Institute in Massachusetts explored the effects of various artemisinin derivatives on connective tissue cells, specifically human dermal fibroblasts. The researchers compared the effects of different treatments, including Artemisia teas, on fibroblast viability and the expression of fibrotic marker genes. The study found that Artemisia annua, the natural source of artemisinin, had a greater anti-fibrotic effect than artemisinin alone, but was less effective than Artemisia afra. The findings suggest that these treatments can yield different responses in human dermal fibroblasts, including those related to fibrosis and remodeling of fibrotic extracellular matrix. [Extracted from the article] |