Abstrakt: |
A report from the First Affiliated Hospital of Bengbu Medical College in China discusses the role of the prostaglandin (PG) family in malignant diseases. Specifically, the researchers highlight the importance of prostaglandin D2 (PGD2) and its receptor (PTGDR2) in tumorigenesis and anti-tumor therapy. They explain that PGD2 signaling through PTGDR2 can inhibit cancer cell survival, proliferation, and migration, as well as reduce resistance to chemotherapy. The review emphasizes the potential of PGD2 and its receptors as targets for effective cancer therapies. [Extracted from the article] |