| Autor: |
NAIK, V. SIVASANKARA, SRAVANI, P., DEEPTHI, P., BHAVANI, C. |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2024, Vol. 15 Issue 3, p1101-1108, 8p |
| Abstrakt: |
INTRODUCTION : Fungi belonging to the Mucoracea family are usually saprophytic. Mucormycosis disease is lately becoming prevalent since the pandemic of COVID --19. Immunosuppression and immunomodulation have long been postulated as potential risk factors for opportunistic systemic fungal infections. Examination of histopathological features, direct microscopy using potassium hydroxide (KOH) and fungal culture are considered to be the traditional diagnostic approaches for Mucormycosis disease. MATERIALS AND METHODS : This was an observational study carried out at a tertiary care hospital for a period of one year. A total of 247 patients with biopsy proven diagnosis of rhino -- maxillary -- orbital mucormycosis were included in this study. Histopathological features were studied and correlation was made with direct microscopy by KOH and fungal culture. RESULTS : Mucormycosis was found to be more prevalent in males (177 cases, 71.66 %) . Age groups mostly affected were between 41 - 50 years (84 cases, 34 %) followed closely by 51 - 60 years (77 cases, 31.17 %). Maxillary sinus (134 cases, 54.25 %) was the most commonly affected site. Non invasive fungal infection was frequently encountered (217 cases, 87.85 %). Direct Microscopy by KOH was positive in 79 cases (31.98 %), while fungal cultures were positive in 65 cases (26.32 %). CONCLUSION : Histological evaluation remains the mainstay of diagnosis in Mucormycosis over the conventional Microbiological techniques. Identification of the disease at an incipient stage is crucial to prevent fatal outcomes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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