| Autor: |
Zinoveva, Anna D., Borisova, Tatiana N., Podchufarova, Valeria A., Novikov, Anton P., Romanycheva, Anna A., Shetnev, Anton A., Titov, Alexander A., Varlamov, Alexey V., Voskressensky, Leonid G. |
| Předmět: |
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| Zdroj: |
Asian Journal of Organic Chemistry; May2024, Vol. 13 Issue 5, p1-6, 6p |
| Abstrakt: |
A three component reaction employing readily available starting materials: 2‐(1‐pyrrolyl)benzylamine, arylglyoxal monohydrates and electron‐deficient alkenes in the synthesis of dipyrrolobenzo[1,2‐a : 2′,1′‐c][1,4]diazepines ‐ previously undescribed system and indolo[2,1‐c]pyrrolo[1,2‐a][1,4]benzodiazepine derivatives have been shown. Domino reactions of pyrrolo[1,2‐a][1,4]benzodiazepines with electron‐deficient alkenes has been proposed as another approach. The applicability of the three‐component reaction for the synthesis of indolizino[8,7‐b]indole derivatives from tryptamine has been studied. The in vitro biological activity of title compounds has been tested. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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