| Abstrakt: |
Introduction: Thyroid eye disease (TED) is the most common extra thyroidal manifestation of Graves' disease. TED is characterized by inflammatory reactions to the orbital and periocular tissues which cause discomfort and pain and also result in eyelid malposition and exophthalmos, distorting self-image and provoking psychological or social problems. The activity and severity of thyroid eye disease is diverse as well. Hence the current study was undertaken to understand the prevalence of various manifestations of Thyroid eye disease and its associated factor, which would guide further in appropriate management and patient care. Methodology: A hospital based cross-sectional study was done in 400 adult patients with thyroid dysfunction attending tertiary care hospital, after obtaining ethical committee clearance. Patients' with-out thyroid dysfunction with other ocular manifestations, incoherent patients and those who were not willing to participate were excluded. Patients were selected by convenient sampling method during study period of February 2020 to February 2023.Detailed systemic medical and ophthalmological examination was done. Data collected using semi structured questionnaire. Statistical analysis was done in SPSS version 20, using student t test and chi-square test with P<0.05 considered as statistically significant. Results: Out of the 400 patients in this study, there were 175(43.5%) males and 225(56.5%) female patients. Age ranges from 18-78 years with mean ± Standard deviation (SD) of age being 48.14 ± 15.82. TED was seen in 168(42%) of patients. CAS score = 3 was seen in 62 (15.5%) patients. Foreign body sensation was the most common eye manifestation seen in 256(64%), followed by dry eye in 171(42.75%). Conclusion: Mean TSH and CAS score was high in patients with TED when compared to patients without TED. Higher mean age, male gender, hypothyroid status, higher mean duration of thyroid disorder, lower free T3, lesser free T4, higher TSH, and smoking were significantly associated with patients with CAS =3. [ABSTRACT FROM AUTHOR] |
