Relationship between oral lesions and severe SARS‐CoV‐2 infection in intensive care unit patients.

Autor: Favia, Gianfranco, Barile, Giuseppe, Tempesta, Angela, Copelli, Chiara, Novielli, Gianluigi, Dell'Olio, Fabio, Capodiferro, Saverio, Spirito, Francesca, Brienza, Nicola, Ribezzi, Mario, Vestito, Maria Concetta, Corriero, Alberto, Carpagnano, Elisiana, Moschetta, Antonio, Chironna, Maria, Loconsole, Daniela, Centrone, Francesca, Quadri, Mir Faeq Ali, Tartaglia, Gianluca Martino, Limongelli, Luisa
Předmět:
Zdroj: Oral Diseases; Apr2024, Vol. 30 Issue 3, p1296-1303, 8p
Abstrakt: Objective: Oral lesions received increased attention as likely new signs or secondary manifestations of COVID‐19. Therefore, we clinically examined oral cavity of patients with COVID‐19 and investigated oral lesions and patient comorbidities as possible risk factors of COVID‐19 disease outcome. Methods: From January to March 2022, a prospective study was conducted by recruiting all COVID‐19 patients admitted to the Intensive Care Unit and Respiratory Intensive Care Unit of Maxi‐Emergencies Hospital in Bari, Italy. Results: From the enrolled 103 COVID‐19 patients, 46.6% were females and 53.4% were males. Findings show that risk of presenting with severe COVID‐19 disease was higher in patients who developed oral lesions related to COVID‐19 than those with no oral lesions (RR = 7.998, p =.002). Next, patients with concomitant autoimmune diseases were at higher risk of a negative COVID‐19 disease outcome than those without comorbidities (OR = 8.838, p =.026). Conclusions: COVID‐19‐related lesions of oral mucosa should not be ignored as they can be early and easily detectable signs of severe COVID‐19 disease condition, thus, serving as a prevention measure for any potential unfortunate event. Findings of this study, without implying causation, offer a direction for future investigations that aim to confirm the presence of specific oral lesions in COVID‐19 patients as signs of severe disease progression. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index