New updates in sarcoidosis research: defining and renewing the quest.

Autor: Bonham, Catherine A., Sharp, Michelle
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Zdroj: American Journal of Physiology: Lung Cellular & Molecular Physiology; Apr2024, Vol. 326 Issue 4, pL480-L481, 2p
Abstrakt: Sarcoidosis is a complex disease with many unanswered questions. Its heterogeneity, including various organ manifestations and treatment responses, makes it difficult to study. Recent research has focused on different clinical phenotypes, radiomics, genomics, and the role of race and genetic ancestry in understanding sarcoidosis. Studies have explored genetic risk factors, radiomic features, immunophenotypes, and the architecture of granulomas. While genetics play a role, they do not fully explain the disease, and environmental factors and disparities based on race and ancestry also need to be considered. Standardized definitions, collaborations, and diverse cohorts are needed to advance our understanding of sarcoidosis. [Extracted from the article]
Databáze: Complementary Index