Uncovering the Unseen: Bordetella hinzii Emerges in a Lung Transplant Recipient.

Autor: Vulturar, Damiana-Maria, Pilmis, Benoît, Rouzaud, Claire, Gigandon, Anne, Dauriat, Gaëlle, Feuillet-Soummer, Séverine, Moaca, Liviu-Stefan, Fadel, Elie, Mercier, Olaf, Fabre, Dominique, Lortholary, Olivier, Le Pavec, Jérôme
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Zdroj: International Journal of Molecular Sciences; May2024, Vol. 25 Issue 9, p4708, 6p
Abstrakt: Bordetella hinzii (B. hinzii), a Gram-negative bacillus commonly associated with respiratory infections in animals, has garnered attention for its sporadic cases in humans, particularly in immunocompromised individuals. Despite its opportunistic nature, there remains limited understanding regarding its pathogenicity, diagnostic challenges, and optimal treatment strategies, especially in the context of immunosuppression. Herein, we present the first documented case of acute bronchitis caused by B. hinzii in an immunocompromised patient following double-lung transplantation. The patient, a former smoker with sarcoidosis stage IV, underwent transplant surgery and subsequently developed a febrile episode, leading to the identification of B. hinzii in broncho-alveolar lavage samples. Antimicrobial susceptibility testing revealed resistance to multiple antibiotics, necessitating tailored treatment adjustments. Our case underscores the importance of heightened awareness among clinicians regarding B. hinzii infections and the imperative for further research to elucidate its epidemiology and optimal management strategies, particularly in immunocompromised populations. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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