| Abstrakt: |
A recent study conducted by researchers at the University of Toronto explores the potential role of thyroid hormone receptors (THR) in breast cancer. The study suggests that THRb, a specific type of thyroid hormone receptor, may act as a tumor suppressor and could be a potential prognostic biomarker and therapeutic target in breast cancer. The researchers found that higher expression of THRb1 was associated with a lower risk of breast cancer recurrence and longer overall survival. Further research is needed to validate THRb as an independent prognostic biomarker and explore its potential as a predictive biomarker for response to endocrine therapy and/or chemotherapy. Additionally, the study suggests that THRb agonists could be investigated as anti-cancer agents. [Extracted from the article] |
