Reports from Iowa State University Highlight Recent Findings in Steroid Receptors (Comprehensive Characterization of the Effect of Mineralocorticoid Receptor Antagonism With Spironolactone On the Renin-angiotensin-aldosterone System In Healthy...).

Předmět:	STEROID receptors MINERALOCORTICOID receptors RENIN-angiotensin system SPIRONOLACTONE DNA-binding proteins
Zdroj:	Drug Week; 5/17/2024, p1884-1884, 1p
Abstrakt:	A recent study conducted at Iowa State University examined the effects of spironolactone, a medication used to treat various conditions, on the renin-angiotensin-aldosterone system (RAAS) in healthy dogs. The study found that spironolactone increased serum aldosterone concentration and impacted other biomarkers of the RAAS in the dogs. The researchers concluded that a dosage of 4 mg/kg/day of spironolactone was safe and well-tolerated in healthy dogs. This study provides valuable insights into the effects of spironolactone on the RAAS in canines. [Extracted from the article]
Databáze:	Complementary Index
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