Study Data from Federal University Pernambuco Update Understanding of Antimicrobials [First Report of Ocellatin-VT from the Skin Secretion of Leptodactylus vastus Lutz (Amphibia: Leptodactylidae)].

Předmět:	LEPTODACTYLIDAE AMPHIBIANS ANTI-infective agents SECRETION PEPTIDE antibiotics ANTIMICROBIAL peptides
Zdroj:	Hematology Week; 5/14/2024, p2659-2659, 1p
Abstrakt:	A study conducted at Federal University Pernambuco in Brazil has discovered a new antimicrobial peptide called ocellatin-VT in the skin secretion of Leptodactylus vastus, a type of frog. The peptide was found to be active against both non-resistant and multidrug-resistant bacteria, particularly inhibiting the growth of Gram-negative bacteria such as Acinetobacter baumannii and Escherichia coli. Ocellatin-VT showed low toxicity to melanoma cells and minimal hemolytic activity. This research contributes to the ongoing efforts to find new drug candidates to combat antimicrobial resistance. [Extracted from the article]
Databáze:	Complementary Index
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