| Abstrakt: |
Introduction: Diabetic kidney disease (DKD) is a major long-term complication of type 2 diabetes(T2DM) and the most common cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) worldwide. The study aims to assess the prevalence of kidney involvement among T2DM patients, and determine the predictive value of HbA1C and albumin- creatinine ratio (ACR) for declining GFR. Methodology: The study is a cross-sectional analysis of 106 patients diagnosed with T2DM. Data collection included medical record review, face-to-face interviews, blood and urine sample analysis, and calculation of eGFR. Patients were classified based on GFR and urinary ACR, and those with kidney involvement were identified. Result: Out of 106 T2DM patients, 46.2% had kidney involvement based on elevated ACR. Among these, 28.6% had a GFR <15 ml/min/1.73m² and were on hemodialysis. Significant differences were observed between the patients with kidney involvement and the patients without kidney involvement in terms of age, HbA1C levels, ACR, GFR, duration of diabetes, and tobacco use history. ROC curve analysis showed that HbA1C and ACR were reliable markers for predicting kidney involvement. Conclusion: Patients with T2DM and kidney involvement have higher HbA1C levels, greater albuminuria (ACR), reduced GFR, and longer duration of diabetes compared to those without kidney involvement. HbA1C and ACR can serve as useful markers for predicting kidney involvement in T2DM patients. [ABSTRACT FROM AUTHOR] |
