| Autor: |
Thu Hoa, Nguyen Thi, Cham, Ba Thi, Hong Nhung, Le Thi, Kim Anh, Nguyen Thi, Hiep, Nguyen Tuan, Hoang Anh, Nguyen Thi, Thuy, Trinh Thi, Delfino, Domenico V, Thuy Linh, Nguyen Thi |
| Předmět: |
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| Zdroj: |
Journal of Biologically Active Products from Nature; Apr2024, Vol. 14 Issue 2, p230-237, 8p |
| Abstrakt: |
The phytochemical investigation of Gnetum latifolium var. funiculare Markgr. resulted in the isolation of five compounds (1-5). Their structures were determined as bisisorhapotingenin A (1), genetifolin E (2), genetifolin K (3), piceid (4), and isorhapontin (5) based on extensive analyses of HR-ESI-MS, 1D and 2D NMR spectra. All of these five isolated compounds were evaluated for their inhibition effect on lipopolysaccharide (LPS)- induced nitric oxide (NO) production in RAW264.7 macrophages. Among them, two compounds (1 and 3) showed moderate effect on NO production inhibition in LPS-activated RAW264.7 cells with the IC50 values of 53.80 and 93.94 μM, respectively. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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