Abstrakt: |
A recent study conducted at the University of Virginia provides new insights into Neisseria gonorrhoeae, the bacterium that causes gonorrhea. The research found that Neisseria gonorrhoeae has developed mechanisms to resist killing by neutrophils, which are immune cells that respond to infection. One such mechanism is sialylation, where the bacterium sialylates its surface sugars with sialic acid obtained from the host. This modification enables the bacterium to resist complement-mediated killing and suppress neutrophil activation. The findings have implications for the development of vaccines and therapeutics for gonorrhea. [Extracted from the article] |