Reports on Immunology Findings from University of Oxford Provide New Insights (Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data).
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| Zdroj: | Health & Medicine Week; 5/10/2024, p4645-4645, 1p |
| Abstrakt: | A report from the University of Oxford discusses the role of B cells in adaptive immunity and the discrepancies between flow cytometry-defined B cell subsets and their molecular signatures. The study analyzes single-cell multi-omics data from healthy individuals and patients with various diseases to understand the level of cellular contamination within flow cytometric-based gating. The research highlights the heterogeneity of flow cytometric-defined B cell populations and the need to reconsider subset definitions in the literature. The study proposes leveraging single-cell multi-omics data as a powerful tool for characterizing B cell subsets. [Extracted from the article] |
| Databáze: | Complementary Index |
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