Abstrakt: |
A study conducted by the National Research Council (CNR) in Milan, Italy, explores the potential of "linear-shaped" diaryl pyrazines as antiprotozoal agents. The researchers used a chemoenzymatic approach to synthesize these compounds, starting from commercially available aromatic aldehydes. The pyrazines were then tested for their leishmanicidal and antiplasmodial activity in vitro. This research provides valuable insights into the development of novel drugs for the treatment of parasitic diseases. [Extracted from the article] |