Synthesis of New N-[β-(Hetero)arylethyl]benzimidazole-2-carbothioamides and Their Analogues as Anti-Infective Agents and Compounds with Possible Neuro(psycho)tropic and Anticancer activity.

Autor: Divaeva, L. N., Zubenko, A. A., Morkovnik, A. S., Sochnev, V. S., Svyatogorova, A. E., Klimenko, A. I.
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Zdroj: Russian Journal of General Chemistry; Feb2024, Vol. 94 Issue 2, p341-351, 11p
Abstrakt: Representatives of previously unknown benzimidazole-2-carbothioamides containing N-β-(hetero)arylethyl groups in the thioamide fragment were synthesized. Such structures are interesting as agents with anti-infective, neuro(psycho)tropic and anticancer activity. It was shown that some representatives with an additional highly basic site in the N-substituent can show high protistocidal activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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