The Thousand Faces of Invasive Group A Streptococcal Infections: Update on Epidemiology, Symptoms, and Therapy.
| Autor: | Mercadante, Stefania, Ficari, Andrea, Romani, Lorenza, De Luca, Maia, Tripiciano, Costanza, Chiurchiù, Sara, Calo Carducci, Francesca Ippolita, Cursi, Laura, Di Giuseppe, Martina, Krzysztofiak, Andrzej, Bernardi, Stefania, Lancella, Laura |
|---|---|
| Předmět: |
STREPTOCOCCAL disease treatment
STREPTOCOCCAL disease prevention ANTIBIOTICS STREPTOCOCCAL disease diagnosis PREVENTION of epidemics THERAPEUTIC use of monoclonal antibodies PUBLIC health surveillance INTRAVENOUS immunoglobulins NONSTEROIDAL anti-inflammatory agents VACCINE development CHEMOPREVENTION MICROBIAL virulence BETA lactam antibiotics DRUG resistance in microorganisms FLUID therapy STREPTOCOCCUS TOXIC shock syndrome CLINDAMYCIN STREPTOCOCCAL diseases LINEZOLID ANTIBIOTIC prophylaxis COVID-19 pandemic MICROBIAL genetics TUMOR necrosis factors INTERLEUKINS DISEASE incidence DISEASE risk factors DISEASE complications CHEMICAL inhibitors SYMPTOMS CHILDREN |
| Zdroj: | Children; Apr2024, Vol. 11 Issue 4, p383, 13p |
| Abstrakt: | Invasive infections caused by Streptococcus pyogfenes (iGAS), commonly known as Group A Streptococcus, represent a significant public health concern due to their potential for rapid progression and life-threatening complications. Epidemiologically, invasive GAS infections exhibit a diverse global distribution, affecting individuals of all ages with varying predisposing factors. The pathogenesis of invasive GAS involves an array of virulence factors that contribute to tissue invasion, immune evasion, and systemic dissemination. In pediatrics, in the last few years, an increase in iGAS infections has been reported worldwide becoming a challenging disease to diagnose and treat promptly. This review highlights the current knowledge on pathogenesis, clinical presentations, and therapeutic approaches for iGAS in children. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
| Externí odkaz: |
|