The relationship of ABO and Lewis blood groups in patients with urinary tract infection.

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Zdroj: Iranian Journal of War & Public Health; Winter2024, Vol. 16 Issue 1, p1-13, 13p
Abstrakt: Aims. Urinary tract infection considers as one the most common adult bacterial infection worldwide. Antigens of ABO and Lewis blood groups may influence bacterial adherence and lead to an increase in the frequency of UTI in adults. The aim of this study to evaluate the relationship of ABO, and Lewis blood groups with UTI. As well as to determine the main microbial cause of UTI and its association and distribution with blood group antigens. Method. Blood sample of 80 UTI patients and 50 healthy persons used for determination of ABO and Lewis blood groups by agglutination assay. Urine samples of UTI patients were cultured and identified based on culture characteristics, gram staining and biochemical tests. Results. Urinary tract infection was significantly highest in patients with O blood group (42.5%) Lewis (a-b-) phenotype (38.8%) as compared with other blood groups and with control group. Escherichia coli was found to be the commonest bacterial isolates observed in UTI patients. Also E. coli was significantly highest among UTI patients with O blood group and Lewis (a-b-) phenotype. Conclusion. The study concludes that ABO and Lewis blood types as well as secretor status have a significant association with susceptibility to infection with urinary tract infection. O blood group as well as Lewis (a-b-) phenotype have a higher susceptibility to urinary tract infection. Escherichia coli was the main causative agent of UTI and it was statistically significantly highest in patients with O blood group and Lewis (a-b-) phenotype. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index