Effect of 12 Weeks Incremental Resistance Training on Serum Levels of Myostatin, Follistatin, and IGF-I in Sedentary Elderly Men.
| Autor: | H., Barzegari Marvast, A., Akbarnejad, J., Norouzi |
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| Předmět: |
PHOTON absorptiometry
CARRIER proteins T-test (Statistics) MYOSTATIN SEDENTARY lifestyles STATISTICAL sampling ENZYME-linked immunosorbent assay BODY composition PSYCHOLOGY of men RANDOMIZED controlled trials ANALYSIS of covariance RESISTANCE training PRE-tests & post-tests SOMATOMEDIN DATA analysis software SARCOPENIA NONPARAMETRIC statistics MENTAL depression SOCIAL isolation BLOOD |
| Zdroj: | Iranian Journal of War & Public Health; Winter2024, Vol. 16 Issue 1, p1-8, 8p |
| Abstrakt: | Aims Numerous studies have established that resistance training is highly effective in preventing and addressing age-related muscle loss (sarcopenia) by enhancing the physiological function of skeletal muscle tissue. Thus, the objective of this study was to assess the impact of 12 weeks of incremental resistance training on the serum levels of myostatin, follistatin, and insulin-like growth factor-1 (IGF-I) in sedentary elderly men. Materials & Methods Thirty sedentary elderly men voluntarily participated in this semiexperimental study and were randomly assigned to either a control group (15 men) with an average age of 62.1±3.7 years and weight of 85.1±7.7 kg, or a resistance training group (15 men) with an average age of 61.3±1.6 years and weight of 82.3±7.8 kg. The resistance training group undertook a 12-week training protocol, while the control group did not engage in any training program during this time. Blood samples and body composition measurements (using dual X-ray absorptiometry) were taken before the study commenced and 48 hours after the last training session concluded. Serum levels of myostatin, follistatin, and IGF-I were determined using the ELISA method. An independent t-test was employed to establish statistical significance between the groups, utilizing SPSS 21 software. Findings After 12 weeks of resistance training, there was a significant decrease in serum myostatin levels and significant increases in serum follistatin and IGF-I levels in comparison to the control group (p=0.05). Conclusion Incremental resistance training proves to be an effective intervention for preventing sarcopenia in elderly individuals by decreasing serum levels of myostatin and increasing serum levels of follistatin and IGF-I. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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