| Autor: |
Guo-ying Liu, Lu-ning Tang, Jun-hua Li, Sen Yang, Ming Chen |
| Předmět: |
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| Zdroj: |
Chemical Communications; 4/28/2024, Vol. 60 Issue 33, p4471-4474, 4p |
| Abstrakt: |
Herein, a palladium-catalyzed regioselective alkynylation, esterification, and amination of allylic gem-difluorides via C--F bond activation/transmetallation/β-C elimination or nucleophilic attack has been achieved. This innovative protocol showcases an extensive substrate range and operates efficiently under mild reaction conditions, resulting in high product yields and Z-selectivity. Particularly noteworthy is its exceptional tolerance towards a wide array of functional groups. This developed methodology provides effective and convenient routes to access a diverse array of essential fluorinated enynes, esters and amines. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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