Predicting Leptospirosis Outcomes in Dogs with the Simplified Acute Physiology Score.

Autor: Laptev, Sergey, Pimenov, Nikolai, Pozyabin, Sergej, Ivanyuk, Vasily, Marzanova, Saida, Permyakova, Kristina, Selina, Marina
Předmět:
Zdroj: Advancements in Life Sciences; Feb2024, Vol. 11 Issue 1, p173-181, 9p
Abstrakt: Background: Leptospirosis is a serious infectious disease affecting dogs, caused by the spirochete bacterium Leptospira. Understanding the prognosis and severity of the disease is essential for effective clinical management. This study aimed to assess the use of the PIRO and SAPS scales in predicting the outcome of leptospirosis in dogs. Methods: The study involved 24 dogs diagnosed with leptospirosis and a control group of 22 healthy dogs. Clinical assessments were conducted, and scores on the PIRO and SAPS scales were assigned within 24 hours of admission. Statistical analyses, including correlation and regression, were employed to evaluate the relationship between scale scores and disease outcomes. Results: In dogs with leptospirosis, SAPS scale scores exhibited a strong positive correlation with disease outcomes, indicating a robust association. Scores on the SAPS scale were associated with the severity of the disease, with specific score ranges indicative of a moderate, severe, or fatal outcome. The PIRO scale also demonstrated a substantial correlation with SAPS scores and disease prognosis. In cases where the immune system was compromised, protective mechanisms activated with a delay, increasing the risk of fatality. Conclusion: The PIRO and SAPS scales provide valuable tools for assessing the severity and predicting the outcome of leptospirosis in dogs. These scales offer clinicians a means to promptly evaluate the risk of physiological disruptions and sepsis complications in dogs with leptospirosis, ultimately aiding in clinical decision-making and treatment planning. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index